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Evaluation of a rapid antigen test (Panbio™ COVID-19 Ag rapid test device) for SARS-CoV-2 detection in asymptomatic close contacts of COVID-19 patien…

2021

Objectives There is limited information on the performance of rapid antigen detection (RAD) tests to identify SARS-CoV-2-infected asymptomatic individuals. In this field study, we evaluated the Panbio™ COVID-19 Ag Rapid Test Device (Abbott Diagnostics, Jena, Germany) for this purpose. Methods A total of 634 individuals (355 female; median age, 37 years; range, 9–87) were enrolled. Two nasopharyngeal swabs were collected from household (n = 338) and non-household contacts (n = 296) of COVID-19 cases. RAD testing was carried out at the point of care. The RT-PCR test used was the TaqPath COVID-19 Combo Kit (Thermo Fisher Scientific, MA, USA). Results Household contacts were tested at a median …

0301 basic medicineMicrobiology (medical)AdultMale2019-20 coronavirus outbreakmedicine.medical_specialtyCoronavirus disease 2019 (COVID-19)Rapid antigen detection testAdolescentSevere acute respiratory syndrome coronavirus 2 (SARS-CoV-2)Point-of-Care Systems030106 microbiologyTest sensitivityImmunologic TestsAsymptomaticSensitivity and Specificity03 medical and health sciencesYoung Adult0302 clinical medicineCOVID-19 TestingInternal medicineMedicineHumans030212 general & internal medicineChildAntigens ViralAsymptomatic InfectionsAgedAged 80 and overImmunoassayFamily Characteristicsbusiness.industrySARS-CoV-2COVID-19General MedicineMiddle AgedTest (assessment)AsymptomaticResearch NoteInfectious DiseasesRapid antigen testCOVID-19 Nucleic Acid TestingClose contactsFemalemedicine.symptomContact TracingbusinessContact tracingClinical Microbiology and Infection
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